药典知识与色谱柱选型对照
United States Pharmacopeia–National Formulary(USP–NF)
对色谱方法采用独特的"L 代号"体系指定 HPLC 填料(如 L1=C18)。药典只指定代号不指定品牌,凡符合该代号定义的柱子即可使用——这是本页选型对照的基础。
访问 USP 官网 ↗European Pharmacopoeia(Ph. Eur.)
38 个成员国及欧盟法定采用,具法律约束力。固定相以通用描述指定并配套系统适用性要求,是欧盟市场准入的质量基准。
访问 EDQM 官网 ↗日本薬局方(Japanese Pharmacopoeia)
与 USP、EP 同为 ICH 三方药典协调(PDG)成员,通用检测方法持续协调统一。色谱条件以文字描述固定相,选型逻辑与 ChP 类似。
访问 PMDA 官网 ↗| 代号 | 英文释义(USP 原文) | 中文释义 |
|---|---|---|
| L1 | Octadecyl silane chemically bonded to porous or nonporous silica particles, superficially porous particles, or ceramic microparticles, 1.5–10 μm in diameter, or a monolithic silica rod. | 十八烷基硅烷化学键合于多孔或非多孔硅胶颗粒、表面多孔颗粒或陶瓷微粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L2 | Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 μm in diameter. | 十八烷基硅烷化学键合于受控表面孔隙率的硅胶,该硅胶键合在直径 30-50 μm 的实心球形核心上。 |
| L3 | Porous silica particles or superficially porous particles, 1.5–10 μm in diameter, or a monolithic silica rod. | 多孔硅胶颗粒或表面多孔颗粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L4 | Silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50 μm in diameter. | 受控表面孔隙率的硅胶键合于直径 30-50 μm 的实心球形核心上。 |
| L5 | Alumina of controlled surface porosity bonded to a solid spherical core, 30 to 50 μm in diameter. | 受控表面孔隙率的氧化铝键合于直径 30-50 μm 的实心球形核心上。 |
| L6 | Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 μm in diameter. | 强阳离子交换填料;磺化氟碳聚合物涂覆在直径 30-50 μm 的实心球形核心上。 |
| L7 | Octylsilane chemically bonded to totally porous or superficially porous silica particles, 1.5–10 μm in diameter, or a monolithic silica rod. | 辛基硅烷化学键合于全多孔或表面多孔硅胶颗粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L8 | An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5–10 μm in diameter, or a monolithic silica rod. | 基本为单分子层的氨丙基硅烷化学键合于全多孔硅胶载体,直径 1.5-10 μm;或整体硅胶棒。 |
| L9 | Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 μm in diameter. | 不规则或球形、全多孔硅胶,具有化学键合的强酸性阳离子交换涂层,直径 3-10 μm。 |
| L10 | Nitrile groups chemically bonded to porous silica particles or superficially porous particles, 1.5–10 μm in diameter, or a monolithic silica rod. | 氰基化学键合于多孔硅胶颗粒或表面多孔颗粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L11 | Phenyl groups chemically bonded to porous or superficially porous silica particles, 1.5–10 μm in diameter, or a monolithic silica rod. | 苯基化学键合于多孔或表面多孔硅胶颗粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L12 | A strong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core, 30 to 50 μm in diameter. | 强阴离子交换填料,由季胺化学键合到直径 30-50 μm 的实心硅胶球形核心上制成。 |
| L13 | Trimethylsilane chemically bonded to porous silica particles, 3 to 10 μm in diameter. | 三甲基硅烷化学键合于多孔硅胶颗粒,直径 3-10 μm。 |
| L14 | Silica gel having a chemically bonded, strongly basic quaternary ammonium anion-exchange coating, 5 to 10 μm in diameter. | 具有化学键合强碱性季铵阴离子交换涂层的硅胶,直径 5-10 μm。 |
| L15 | Hexylsilane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. | 己基硅烷化学键合于全多孔硅胶颗粒,直径 3-10 μm。 |
| L16 | Dimethylsilane chemically bonded to porous silica particles, 5 to 10 μm in diameter. | 二甲基硅烷化学键合于多孔硅胶颗粒,直径 5-10 μm。 |
| L17 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene–divinylbenzene copolymer in the hydrogen form, 6 to 12 μm in diameter. | 强阳离子交换树脂,由氢型磺化交联苯乙烯-二乙烯苯共聚物组成,直径 6-12 μm。 |
| L18 | Amino and cyano groups chemically bonded to porous silica particles, 3 to 10 μm in diameter. | 氨基和氰基化学键合于多孔硅胶颗粒,直径 3-10 μm。 |
| L19 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 5–15 μm in diameter. | 强阳离子交换树脂,由钙型磺化交联苯乙烯-二乙烯苯共聚物组成,直径 5-15 μm。 |
| L20 | Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5–10 μm in diameter, or a monolithic silica rod. | 二羟基丙烷基团化学键合于多孔硅胶或杂化颗粒,直径 1.5-10 μm;或整体硅胶棒。 |
| L21 | A rigid, spherical styrenedivinylbenzene copolymer 3 to 30 μm in diameter. | 刚性球形苯乙烯-二乙烯苯共聚物,直径 3-30 μm。 |
| L22 | A cation-exchange resin made of porous polystyrene gel with sulfonic acid groups, 5–15 μm in diameter. | 由带磺酸基的多孔聚苯乙烯凝胶制成的阳离子交换树脂,直径 5-15 μm。 |
| L23 | An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups, 7–12 μm in size. | 由带季铵基的多孔聚甲基丙烯酸酯或聚丙烯酸酯凝胶制成的阴离子交换树脂,粒径 7-12 μm。 |
| L24 | Polyvinylalcohol chemically bonded to porous silica particle, 5 μm in diameter. [Note—Available as YMC-Pack PVA-SIL manufactured by YMC Co., Ltd. and distributed by Waters Corp. (www.waters.com).] | 聚乙烯醇化学键合于多孔硅胶颗粒,直径 5 μm。注:可获得 YMC Co., Ltd. 生产、Waters Corp. 分销的 YMC-Pack PVA-SIL。 |
| L25 | Packing having the capacity to separate compounds with a molecular weight range from 100–5000 (as determined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups) was found suitable. | 具有按分子量范围 100-5000(以聚氧化乙烯测定)分离化合物能力的填料,适用于中性、阴离子和阳离子水溶性聚合物。适用材料为以聚甲基丙烯酸酯树脂为基体、用多羟基醚交联的材料(表面含有少量残留羧基官能团)。 |
| L26 | Butyl silane chemically bonded to totally porous or superficially porous silica particles, 1.5–10 μm in diameter. | 丁基硅烷化学键合于全多孔或表面多孔硅胶颗粒,直径 1.5-10 μm。 |
| L27 | Porous silica particles, 30 to 50 μm in diameter. | 多孔硅胶颗粒,直径 30-50 μm。 |
| L28 | A multifunctional support, which consists of a high purity, 100 Å, spherical silica substrate that has been bonded with anionic exchanger, amine functionality in addition to a conventional reversed phase C8 functionality. | 多功能载体,由高纯度 100 Å 球形硅胶基质组成;除常规反相 C8 官能团外,还键合有阴离子交换基团和胺官能团。 |
| L29 | Gamma alumina, reverse-phase, low carbon percentage by weight, alumina-based polybutadiene spherical particles, 5 μm in diameter with a pore volume of 80 Å. | γ-氧化铝,反相、低碳含量的氧化铝基聚丁二烯球形颗粒,直径 5 μm,孔体积 80 Å。 |
| L30 | Ethyl silane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. | 乙基硅烷化学键合于全多孔硅胶颗粒,直径 3-10 μm。 |
| L31 | A hydroxide-selective, strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5-μm macroporous particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. | 氢氧根选择性强阴离子交换树脂;季胺键合于乳胶颗粒,乳胶颗粒附着于 8.5 μm 大孔颗粒核心上,核心孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成。 |
| L32 | A chiral ligand-exchange packing–l-proline copper complex covalently bonded to irregularly shaped silica particles, 5 to 10 μm in diameter. | 手性配体交换填料;L-脯氨酸铜络合物共价键合于不规则形硅胶颗粒,直径 5-10 μm。 |
| L33 | Packing having the capacity to separate dextrans by molecular size over a range of 4,000 to 500,000 Da. It is spherical, silica-based, and processed to provide pH stability. [Note—Available as TSK-GEL G4000SWxl from Tosoh Bioscience (www.tosohbioscience.com).] | 具有按分子尺寸在 4,000-500,000 Da 范围内分离葡聚糖能力的填料。该填料为球形、硅胶基,并经处理以提供 pH 稳定性。注:可获得 Tosoh Bioscience 的 TSK-GEL G4000SWxl。 |
| L34 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene–divinylbenzene copolymer in the lead form, 7 to 9 μm in diameter. | 强阳离子交换树脂,由铅型磺化交联苯乙烯-二乙烯苯共聚物组成,直径 7-9 μm。 |
| L35 | A zirconium-stabilized spherical silica packing with a hydrophilic (diol-type) molecular monolayer bonded phase having a pore size of 150 Å. | 锆稳定球形硅胶填料,具有亲水性(二醇型)分子单层键合相,孔径 150 Å。 |
| L36 | A 3,5-dinitrobenzoyl derivative of l-phenylglycine covalently bonded to 5-μm aminopropyl silica. | L-苯甘氨酸的 3,5-二硝基苯甲酰衍生物,共价键合于 5 μm 氨丙基硅胶。 |
| L37 | Packing having the capacity to separate proteins by molecular size over a range of 2,000 to 40,000 Da. It is a polymethacrylate gel. | 具有按分子尺寸在 2,000-40,000 Da 范围内分离蛋白质能力的填料。该填料为聚甲基丙烯酸酯凝胶。 |
| L38 | A methacrylate-based size-exclusion packing for water-soluble samples. | 用于水溶性样品的甲基丙烯酸酯基体积排阻填料。 |
| L39 | A hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin. | 全多孔球形树脂的亲水性聚羟基甲基丙烯酸酯凝胶。 |
| L40 | Cellulose tris-3,5-dimethylphenylcarbamate-coated, porous silica particles, 3–20 μm in diameter. | 纤维素三(3,5-二甲基苯基氨基甲酸酯)涂覆的多孔硅胶颗粒,直径 3-20 μm。 |
| L41 | Immobilized α1-acid glycoprotein on spherical silica particles, 5 μm in diameter. | α1-酸性糖蛋白固定化于球形硅胶颗粒,直径 5 μm。 |
| L42 | Octylsilane and octadecylsilane groups chemically bonded to porous silica particles, 5 μm in diameter. | 辛基硅烷和十八烷基硅烷基团化学键合于多孔硅胶颗粒,直径 5 μm。 |
| L43 | Pentafluorophenyl groups chemically bonded to porous or superficially porous silica particles by a propyl spacer, 1.5–10 μm in diameter. | 五氟苯基通过丙基间隔臂化学键合于多孔或表面多孔硅胶颗粒,直径 1.5-10 μm。 |
| L44 | A multifunctional support, which consists of a high purity, 60 Å, spherical silica substrate that has been bonded with a cationic exchanger, sulfonic acid functionality in addition to a conventional reversed phase C8 functionality. | 多功能载体,由高纯度 60 Å 球形硅胶基质组成;除常规反相 C8 官能团外,还键合有阳离子交换基团和磺酸官能团。 |
| L45 | Beta cyclodextrin, R,S-hydroxypropyl ether derivative, bonded to porous silica particles, 3–10 μm in diameter. | β-环糊精 R,S-羟丙基醚衍生物,键合于多孔硅胶颗粒,直径 3-10 μm。 |
| L46 | Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads, about 9 to 11 μm in diameter. | 聚苯乙烯/二乙烯苯基质与季胺官能化乳胶微珠凝聚而成,直径约 9-11 μm。 |
| L47 | High-capacity anion-exchange microporous substrate, fully functionalized with trimethlyamine groups, 8 μm in diameter. [Note—Available as CarboPac MA1 and distributed by Dionex Corp. (www.dionex.com).] | 高容量阴离子交换微孔基质,完全以三甲胺基团官能化,直径 8 μm。注:可获得 Dionex Corp. 分销的 CarboPac MA1。 |
| L48 | Sulfonated, cross-linked polystyrene with an outer layer of submicron, porous, anion-exchange microbeads, 5 to 15 μm in diameter. | 磺化交联聚苯乙烯,外层为亚微米级多孔阴离子交换微珠,直径 5-15 μm。 |
| L49 | A reversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles, 3 to 10 μm in diameter. [Note—Available as Zirchrom PBD from www.zirchrom.com.] | 反相填料,由在球形多孔氧化锆颗粒上涂覆一薄层聚丁二烯制成,直径 3-10 μm。注:可获得 Zirchrom PBD。 |
| L50 | Multifunction resin with reversed-phase retention and strong anion-exchange functionalities. The resin consists of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 μm in diameter, and a surface area not less than 350 m2 per g. Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene. [Note—Available as OmniPac PAX- 500 and distributed by Dionex Corp. (www.dionex.com).] | 具有反相保留和强阴离子交换功能的多功能树脂。树脂由乙基乙烯苯与 55% 二乙烯苯交联共聚物组成,直径 3-15 μm,比表面积不小于 350 m2/g。基质涂覆有季铵官能化乳胶颗粒,乳胶颗粒由苯乙烯与二乙烯苯交联组成。注:可获得 Dionex Corp. 分销的 OmniPac PAX-500。 |
| L51 | Amylose tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 3–10 μm in diameter. [Note—Available as Chiralpak AD from Chiral Technologies, Inc. (www.chiraltech.com).] | 直链淀粉三(3,5-二甲基苯基氨基甲酸酯)涂覆的多孔球形硅胶颗粒,直径 3-10 μm。注:可获得 Chiral Technologies, Inc. 的 Chiralpak AD。 |
| L52 | A strong cation-exchange resin made of porous silica with sulfopropyl or sulfoethyl groups, 1–10 μm in diameter. | 由带磺丙基或磺乙基的多孔硅胶制成的强阳离子交换树脂,直径 1-10 μm。 |
| L53 | Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 μm diameter. Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers. Capacity not less than 500 μEq/column. [Note— Available as IonPac CS14 distributed by Dionex Corp. (www.dionex.com).] | 弱阳离子交换树脂,由乙基乙烯苯与 55% 二乙烯苯交联共聚物组成,直径 3-15 μm。基质表面接枝有羧酸和/或磷酸官能化单体。容量不小于 500 μEq/柱。注:可获得 Dionex Corp. 分销的 IonPac CS14。 |
| L54 | A size exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads, 5–15 μm in diameter. [Note—Available as Superdex Peptide HR 10/30 from www.gelifesciences.com.] | 体积排阻介质,由葡聚糖共价键合于高度交联的多孔琼脂糖微珠制成,直径 5-15 μm。注:可获得 Superdex Peptide HR 10/30。 |
| L55 | A strong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer, about 5 μm in diameter. [Note— Available as IC-Pak C M/D from Waters Corp. (www.waters.com).] | 强阳离子交换树脂,由涂覆有聚丁二烯-马来酸共聚物的多孔硅胶制成,直径约 5 μm。注:可获得 Waters Corp. 的 IC-Pak C M/D。 |
| L56 | Propyl silane chemically bonded to totally or superficially porous silica particles, 3–10 μm in diameter. [Note—Available as Zorbax SB-C3 from Agilent Technologies (www.agilent.com/chem).] | 丙基硅烷化学键合于全多孔或表面多孔硅胶颗粒,直径 3-10 μm。注:可获得 Agilent Technologies 的 Zorbax SB-C3。 |
| L57 | A chiral-recognition protein, ovomucoid, chemically bonded to silica particles, about 5 μm in diameter, with a pore size of 120 Å. [Note— Available as Ultron ES-OVM from Agilent Technologies (www.agilent.com/chem).] | 手性识别蛋白卵类黏蛋白化学键合于硅胶颗粒,直径约 5 μm,孔径 120 Å。注:可获得 Agilent Technologies 的 Ultron ES-OVM。 |
| L58 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 6 to 30 μm in diameter. [Note—Available as Aminex HPX-87N from Bio-Rad Laboratories, (2000/01 catalog, #125-0143) www.bio-rad.com.] | 强阳离子交换树脂,由钠型磺化交联苯乙烯-二乙烯苯共聚物组成,直径约 6-30 μm。注:可获得 Bio-Rad Laboratories 的 Aminex HPX-87N。 |
| L59 | Packing for the size-exclusion separation of proteins (separation by molecular weight) over the range of 5 to 7000 kDa. The packing is a spherical 1.5- to 10-μm silica or hybrid packing with a hydrophilic coating. | 用于蛋白质体积排阻分离(按分子量分离)的填料,分离范围 5-7000 kDa。该填料为带亲水涂层的球形 1.5-10 μm 硅胶或杂化填料。 |
| L60 | Spherical, porous or superficially porous silica particles, 10 μm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and endcapped. | 球形多孔或表面多孔硅胶颗粒,直径不大于 10 μm,表面经烷基酰胺基团共价改性并封端。 |
| L61 | A hydroxide selective strong anion-exchange resin consisting of a highly cross-linked core of 13-μm microporous particles having a pore size less than 10 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 85-nm diameter microbeads bonded with alkanol quaternary ammonium ions (6%). [Note—Available as Ion Pac AS-11 and AG-11 from Dionex (www.dionex.com).] | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 13 μm 微孔颗粒,孔径小于 10 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;外有由 85 nm 微珠组成的乳胶涂层,微珠键合有烷醇季铵离子(6%)。注:可获得 Dionex 的 Ion Pac AS-11 和 AG-11。 |
| L62 | C30 silane bonded phase on a fully porous spherical silica or on superficially porous particles,1.5 –15 μm in diameter. | C30 硅烷键合相,位于全多孔球形硅胶或表面多孔颗粒上,直径 1.5-15 μm。 |
| L63 | Glycopeptide teicoplanin linked through multiple covalent bonds to a 100-Å units spherical silica. [Note—Available as Astec Chirobiotic T from Supelco (www.sigmaaldrich.com).] | 糖肽替考拉宁通过多个共价键连接到 100 Å 球形硅胶上。注:可获得 Supelco 的 Astec Chirobiotic T。 |
| L64 | Strongly basic anion-exchange resin consisting of 8% cross-linked styrene-divinylbenzene copolymer with a quaternary ammonium group in the chloride form, 45 to 180 μm in diameter. [Note—A suitable grade is available as AG 1-X8 resin chloride form from www.discover.bio-rad.com.] | 强碱性阴离子交换树脂,由 8% 交联苯乙烯-二乙烯苯共聚物组成,带氯型季铵基团,直径 45-180 μm。注:合适级别可获得 Bio-Rad 的 AG 1-X8 resin chloride form。 |
| L65 | Strongly acidic cation-exchange resin consisting of 2% sulfonated cross-linked styrene-divinylbenzene copolymer with a sulfonic acid group in the hydrogen form, 45–250 μm in diameter. [Note—A suitable grade is available as AG 50W-X2 resin hydrogen form from www.bio-rad.com.] | 强酸性阳离子交换树脂,由 2% 磺化交联苯乙烯-二乙烯苯共聚物组成,带氢型磺酸基,直径 45-250 μm。注:合适级别可获得 Bio-Rad 的 AG 50W-X2 resin hydrogen form。 |
| L66 | A crown ether coated on a 5-μm particle size silica gel substrate. The active site is (S)-18-crown-6-ether. [Note—Available as Crownpak CR(+) from www.chiraltech.com.] | 冠醚涂覆于 5 μm 粒径的硅胶基质上。活性位点为 (S)-18-冠-6-醚。注:可获得 Crownpak CR(+)。 |
| L67 | Porous vinyl alcohol copolymer with a C18 alkyl group attached to the hydroxyl group of the polymer, 2 to 10 μm in diameter. [Note—Available as apHera C18 from Supelco (www.sigmaaldrich.com).] | 多孔乙烯醇共聚物,聚合物羟基上连接有 C18 烷基,直径 2-10 μm。注:可获得 Supelco 的 apHera C18。 |
| L68 | Spherical, porous silica, 10 μm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and not endcapped. [Note—Available as SUPELCOSIL SUPLEX pKb-100 from Supelco (www.sigmaaldrich.com).] | 球形多孔硅胶,直径不大于 10 μm,表面经烷基酰胺基团共价改性但未封端。注:可获得 Supelco 的 SUPELCOSIL SUPLEX pKb-100。 |
| L69 | Ethylvinylbenzene/divinylbenzene substrate agglomerated with quaternary amine functionalized 130-nm latex beads, about 6.5 μm in diameter. [Note—Available as CarboPac PA20 from www.dionex.com.] | 乙基乙烯苯/二乙烯苯基质与季胺官能化 130 nm 乳胶微珠凝聚而成,直径约 6.5 μm。注:可获得 CarboPac PA20。 |
| L70 | Cellulose tris(phenyl carbamate) coated on 5-μm silica. [Note—Available as Chiralcel OC-H from www.chiraltech.com.] | 纤维素三(苯基氨基甲酸酯)涂覆于 5 μm 硅胶上。注:可获得 Chiralcel OC-H。 |
| L71 | USP 2025 未收录定义 | — |
| L72 | (S)-phenylglycine and 3,5-dinitroanaline urea linkage covalently bonded to silica. [Note—Available as Sumichiral OA-3300, distributed by www.phenomenex.com.] | (S)-苯甘氨酸与 3,5-二硝基苯胺通过脲键共价键合于硅胶。注:可获得 Phenomenex 分销的 Sumichiral OA-3300。 |
| L73 | USP 2025 未收录定义 | — |
| L74 | A strong anion-exchange resin consisting of a highly cross-linked core of 7- μm macroporous particles having a 100-Å average pore size and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene and an anion-exchange layer grafted to the surface, which is functionalized with alkyl quaternary ammonium ions. [Note—Available as IonPac AS14A from Dionex (www.dionex.com).] | 强阴离子交换树脂,由高度交联核心组成;核心为 7 μm 大孔颗粒,平均孔径 100 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;表面接枝阴离子交换层,并以烷基季铵离子官能化。注:可获得 Dionex 的 IonPac AS14A。 |
| L75 | A chiral-recognition protein, bovine serum albumine (BSA), chemically bonded to silica particles, about 7 μm in diameter, with a pore size of 300 Å. | 手性识别蛋白牛血清白蛋白(BSA)化学键合于硅胶颗粒,直径约 7 μm,孔径 300 Å。 |
| L76 | Silica-based, weak cation-exchange material, 5 μm in diameter. Substrate is surface polymerized polybutadiene–maleic acid to provide carboxylic acid functionalities. Capacity not less than 29 μEq/column. [Note—Available as Metrosep C4-250 from Metrohm (www.metrohm.com).] | 硅胶基弱阳离子交换材料,直径 5 μm。基质表面聚合聚丁二烯-马来酸以提供羧酸官能团。容量不小于 29 μEq/柱。注:可获得 Metrohm 的 Metrosep C4-250。 |
| L77 | Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 6- to 9-μm diameter. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity is not less than 500 μEq/column (4 mm × 25 cm). | 弱阳离子交换树脂,由乙基乙烯苯与 55% 二乙烯苯交联共聚物组成,直径 6-9 μm。基质表面接枝羧酸官能化基团。容量不小于 500 μEq/柱(4 mm x 25 cm)。 |
| L78 | A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and anion-exchange (primary, secondary, or tertiary amino groups) functional groups chemically bonded to porous or nonporous silica or ceramic microparticles, 1.0–50 μm in diameter, or a monolithic rod. [Note—Available as Acclaim Mixed-Mode WAX-1 from Thermo Fisher (www.thermofisher.com).] | 硅烷配体,同时包含反相(长于 C8 的烷基链)和阴离子交换(伯、仲或叔氨基)官能团,化学键合于多孔或非多孔硅胶或陶瓷微粒,直径 1.0-50 μm;或整体棒。注:可获得 Thermo Fisher 的 Acclaim Mixed-Mode WAX-1。 |
| L79 | A chiral-recognition protein, human serum albumin (HSA), chemically bonded to silica particles, about 5 μm in diameter. | 手性识别蛋白人血清白蛋白(HSA)化学键合于硅胶颗粒,直径约 5 μm。 |
| L80 | Cellulose tris(4-methylbenzoate)-coated, porous, spherical, silica particles, 5–20 μm in diameter. | 纤维素三(4-甲基苯甲酸酯)涂覆的多孔球形硅胶颗粒,直径 5-20 μm。 |
| L81 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 9-μm porous particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 70-nm diameter microbeads (6% cross-linked) bonded with alkanol quaternary ammonium ions. [Note—A suitable column is Dionex IonPac AS11-HC available from www.thermofisher.com.] | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 9 μm 多孔颗粒,孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;外有由 70 nm 微珠(6% 交联)组成的乳胶涂层,微珠键合有烷醇季铵离子。注:合适色谱柱为 Dionex IonPac AS11-HC。 |
| L82 | Polyamine chemically bonded to cross-linked polyvinyl alcohol polymer, 5 μm in diameter. [Note—Available as Asahipak NH2P-50 from www.shodex.com.] | 多胺化学键合于交联聚乙烯醇聚合物,直径 5 μm。注:可获得 Asahipak NH2P-50。 |
| L83 | A hydroxide-selective, strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 10.5-μm microporous particles of 10-Å pore size, and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. | 氢氧根选择性强阴离子交换树脂;季胺键合于乳胶颗粒,乳胶颗粒附着于 10.5 μm 微孔颗粒核心上,核心孔径 10 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成。 |
| L84 | Weak cation-exchange resin consisting of ethyvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 5 μm in diameter. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity NLT 8400 μEq/column (5-mm × 25-cm). | 弱阳离子交换树脂,由乙基乙烯苯与 55% 二乙烯苯交联共聚物组成,直径 5 μm。基质表面接枝羧酸官能化基团。容量不小于 8400 μEq/柱(5 mm x 25 cm)。 |
| L85 | A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and weak cation-exchange (carboxyl groups) functional groups chemically bonded to porous or nonporous particles, 1.0–50 μm in diameter. | 硅烷配体,同时包含反相(长于 C8 的烷基链)和弱阳离子交换(羧基)官能团,化学键合于多孔或非多孔颗粒,直径 1.0-50 μm。 |
| L86 | Fused core particles with a highly polar ligand possessing five hydroxyl groups tethered to the silica gel outer layer, 1.5–5 μm in diameter. | 熔融核颗粒,具有连接于硅胶外层的高极性配体,该配体含五个羟基,直径 1.5-5 μm。 |
| L87 | Dodecyl silane chemically bonded to porous or superficially porous silica particles, 1.5–10 μm in diameter. | 十二烷基硅烷化学键合于多孔或表面多孔硅胶颗粒,直径 1.5-10 μm。 |
| L88 | Glycopeptide vancomycin linked through multiple covalent bonds to 100 Å spherical silica. | 糖肽万古霉素通过多个共价键连接到 100 Å 球形硅胶上。 |
| L89 | Packing having the capacity to separate compounds with a molecular range from 100 to 3000 (as determined by polyethylene oxide), applied to neutral and anionic water-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylated ether (surface contains some residual cationic functional groups). | 具有按分子范围 100-3000(以聚氧化乙烯测定)分离化合物能力的填料,适用于中性和阴离子水溶性聚合物。聚甲基丙烯酸酯树脂基体,经多羟基醚交联(表面含有少量残留阳离子官能团)。 |
| L90 | Amylose tris-[(S)-α-methylbenzyl]carbamate coated on porous, spherical silica particles, 3–10 μm in diameter. | 直链淀粉三[(S)-α-甲基苄基]氨基甲酸酯涂覆于多孔球形硅胶颗粒,直径 3-10 μm。 |
| L91 | Strong anion-exchange resin consisting of monodisperse polystyrene/divinylbenzene beads coupled with quartenary amine. Bead size is 3– 10 μm. | 强阴离子交换树脂,由单分散聚苯乙烯/二乙烯苯微珠与季胺偶联组成。微珠粒径 3-10 μm。 |
| L92 | A strong anion-exchange resin consisting of highly cross-linked 5- to 9-μm macroporous particles having a 100-Å average pore size and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene and an anion-exchange layer grafted to the surface, which is functionalized with alkanol quarternary ammonium ions. | 强阴离子交换树脂,由高度交联的 5-9 μm 大孔颗粒组成,平均孔径 100 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;表面接枝阴离子交换层,并以烷醇季铵离子官能化。 |
| L93 | Cellulose tris(3,5-dimethylphenylcarbamate) reversed-phase chiral stationary-phase coated on 3- or 5-μm silica gel particles. | 纤维素三(3,5-二甲基苯基氨基甲酸酯)反相手性固定相,涂覆于 3 或 5 μm 硅胶颗粒上。 |
| L94 | A strong anion-exchange resin consisting of highly cross-linked 15-μm microporous particles functionalized with very low cross-linked latex (0.5%) to provide alkanol quartenary ammonium ion exchange sites. | 强阴离子交换树脂,由高度交联的 15 μm 微孔颗粒组成,并以极低交联度乳胶(0.5%)官能化,以提供烷醇季铵离子交换位点。 |
| L95 | A highly polar alkyl ligand comprising five hydroxyl groups that are chemically bonded to totally porous or superficially porous silica or a monolithic silica rod. | 高极性烷基配体,含五个羟基,化学键合于全多孔或表面多孔硅胶,或整体硅胶棒。 |
| L96 | Alkyl chain, reversed-phase bonded totally or superficially to porous silica designed to retain hydrophilic and other polar compounds when using highly aqueous mobile phase, including 100% aqueous, 1.5–10 μm in diameter. | 烷基链反相键合于全多孔或表面多孔硅胶,设计用于在高水相流动相(包括 100% 水相)条件下保留亲水性及其他极性化合物,直径 1.5-10 μm。 |
| L97 | Weak cation-exchange resin consisting of a highly cross-linked core of 5.5-μm porous particles having a pore size of 2000 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity NLT 2400 μEq/column (4-mm × 25-cm). | 弱阳离子交换树脂,由高度交联核心组成;核心为 5.5 μm 多孔颗粒,孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成。基质表面接枝羧酸官能化基团。容量不小于 2400 μEq/柱(4 mm x 25 cm)。 |
| L98 | Weak cation-exchange resin consisting of a highly cross-linked core of 8.0-μm microporous particles having an average pore size of 10 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity of NLT 46 μEq/column (4-mm × 5-cm). | 弱阳离子交换树脂,由高度交联核心组成;核心为 8.0 μm 微孔颗粒,平均孔径 10 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成。基质表面接枝羧酸官能化基团。容量不小于 46 μEq/柱(4 mm x 5 cm)。 |
| L99 | Amylose tris-(3,5-dimethylphenylcarbamate), immobilized on porous, spherical, silica particles, 3–5 μm in diameter. | 直链淀粉三(3,5-二甲基苯基氨基甲酸酯)固定化于多孔球形硅胶颗粒,直径 3-5 μm。 |
| L100 | A 55% crosslinked, microporous, hydrophobic resin core (9-μm microporous particles having a pore size of 10 Å) that consists of a bilayer of anion and cation exchange latex. The first layer is fully sulfonated latex (140 nm) and the second layer is fully aminated latex (76 nm). | 55% 交联的微孔疏水树脂核心(9 μm 微孔颗粒,孔径 10 Å),由阴离子交换乳胶和阳离子交换乳胶双层组成。第一层为完全磺化乳胶(140 nm),第二层为完全胺化乳胶(76 nm)。 |
| L101 | Cholesteryl groups chemically bonded to porous or nonporous silica or ceramic microparticles, 1.5–10 μm in diameter, or a monolithic rod. | 胆甾醇基团化学键合于多孔或非多孔硅胶或陶瓷微粒,直径 1.5-10 μm;或整体棒。 |
| L102 | 1-(3,5-Dinitrobenzamido)-1,2,3,4-tetrahydrophenanthrene covalently bonded to porous spherical silica particles, 5–10 μm in diameter. | 1-(3,5-二硝基苯甲酰胺基)-1,2,3,4-四氢菲共价键合于多孔球形硅胶颗粒,直径 5-10 μm。 |
| L103 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 7.5-μm porous particles having a pore size of 2000 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene electrostatically bonded with hyperbranched alkanol quaternary ammonium ions. | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 7.5 μm 多孔颗粒,孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成,并与超支化烷醇季铵离子静电键合。 |
| L104 | Triazol groups chemically bonded to porous silica particles, 1.5–10 μm in diameter. | 三唑基团化学键合于多孔硅胶颗粒,直径 1.5-10 μm。 |
| L105 | A strong anion-exchange resin consisting of highly cross-linked 9-μm supermacroporous (2000 Å) particles functionalized with very low cross-linked latex (0.2%) to provide alkyl quarternary ammonium ion sites. | 强阴离子交换树脂,由高度交联的 9 μm 超大孔(2000 Å)颗粒组成,并以极低交联度乳胶(0.2%)官能化,以提供烷基季铵离子位点。 |
| L106 | Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 5–8 μm diameter, macroporous particles having an average pore size of 100 Å units. Substrate is surface grafted with carboxylic acid and phosphonic acid functional groups. Capacity NLT 2800 μEq/column (4-mm × 25-cm). | 弱阳离子交换树脂,由乙基乙烯苯与 55% 二乙烯苯交联共聚物组成,直径 5-8 μm,为平均孔径 100 Å 的大孔颗粒。基质表面接枝羧酸和膦酸官能团。容量不小于 2800 μEq/柱(4 mm x 25 cm)。 |
| L107 | USP 2025 未收录定义 | — |
| L108 | USP 2025 未收录定义 | — |
| L109 | Spherical particles of porous graphitic carbon, 1.5–30 μm in diameter. | 多孔石墨化碳球形颗粒,直径 1.5-30 μm。 |
| L110 | A strong anion-exchange resin consisting of highly cross-linked 13-μm (less than 10 Å) particles coated with very low cross-linked latex (0.5%) to provide alkanol quaternary ammonium ion exchange sites. | 强阴离子交换树脂,由高度交联的 13 μm(小于 10 Å)颗粒组成,涂覆极低交联度乳胶(0.5%),以提供烷醇季铵离子交换位点。 |
| L111 | USP 2025 未收录定义 | — |
| L112 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 8.5-μm porous particles having a pore size of 2000 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65-nm diameter microbeads (5% crosslinked) bonded with alkanol quaternary ammonium ions. | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 8.5 μm 多孔颗粒,孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;外有由 65 nm 微珠(5% 交联)组成的乳胶涂层,微珠键合有烷醇季铵离子。 |
| L113 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 7.5-μm porous particles having a pore size of 2000 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65-nm diameter microbeads (8% crosslinked) bonded with alkanol quaternary ammonium ions. | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 7.5 μm 多孔颗粒,孔径 2000 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;外有由 65 nm 微珠(8% 交联)组成的乳胶涂层,微珠键合有烷醇季铵离子。 |
| L114 | Sulfobetaine graft-polymerized to totally or superficially porous silica, 1.5–10 μm in diameter, or a monolithic rod. Packing having densely bonded zwitterionic groups with 1:1 charge balance. | 磺基甜菜碱接枝聚合于全多孔或表面多孔硅胶,直径 1.5-10 μm;或整体棒。该填料具有高密度键合的两性离子基团,电荷平衡为 1:1。 |
| L115 | USP 2025 未收录定义 | — |
| L116 | USP 2025 未收录定义 | — |
| L117 | USP 2025 未收录定义 | — |
| L118 | Aqueous polymerized C18 groups on silica particles, 1.2–5 μm in diameter. | 水相聚合的 C18 基团位于硅胶颗粒上,直径 1.2-5 μm。 |
| L119 | Cellulose tris(3,5-dichlorophenylcarbamate), immobilized on porous, spherical silica particles, 3–5 μm in diameter. | 纤维素三(3,5-二氯苯基氨基甲酸酯)固定化于多孔球形硅胶颗粒,直径 3-5 μm。 |
| L120 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 13-μm microporous particles having a pore size of <10 Angstrom units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65-nm diameter microbeads (8% cross-linked) with alkanol quaternary ammonium ions. Capacity NLT 10 μEq/column (4 mm × 5 cm). | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 13 μm 微孔颗粒,孔径小于 10 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成;外有由 65 nm 微珠(8% 交联)组成的乳胶涂层,带烷醇季铵离子。容量不小于 10 μEq/柱(4 mm x 5 cm)。 |
| L121 | A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 11-μm porous particles having a pore size of less than 10 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene electrostatically bonded with hyperbranched alkanol quaternary ammonium ions. | 氢氧根选择性强阴离子交换树脂,由高度交联核心组成;核心为 11 μm 多孔颗粒,孔径小于 10 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成,并与超支化烷醇季铵离子静电键合。 |
| L122 | Sulfobetaine graft-polymerized to totally or superficially porous hydrophilic polymer particles, 1.0–10 μm in diameter, or a monolithic rod. Packing having densely bonded zwitterionic groups with 1:1 charge balance. | 磺基甜菜碱接枝聚合于全多孔或表面多孔亲水性聚合物颗粒,直径 1.0-10 μm;或整体棒。该填料具有高密度键合的两性离子基团,电荷平衡为 1:1。 |
| L123 | Cellulose tris(3-chloro-4-methylphenylcarbamate) coated porous silica particles, 3–20 μm in diameter. | 纤维素三(3-氯-4-甲基苯基氨基甲酸酯)涂覆的多孔硅胶颗粒,直径 3-20 μm。 |
| L124 | Strong cation-exchange resin consisting of sulfonated cross-linked styrene–divinylbenzene in the silver form, average 25 μm in diameter. | 强阳离子交换树脂,由银型磺化交联苯乙烯-二乙烯苯组成,平均直径 25 μm。 |
| L125 | Polyvinyl alcohol polymer gel weak cation-exchange packing material, 3–7 μm porous particles. The surface is polymerized with polybutadiene–maleic acid to provide carboxylic acid functionalities. The capacity is NLT 1 mEq/column. | 聚乙烯醇聚合物凝胶弱阳离子交换填料,3-7 μm 多孔颗粒。表面聚合聚丁二烯-马来酸以提供羧酸官能团。容量不小于 1 mEq/柱。 |
| L126 | Amylose tris (3-chlorophenylcarbamate), immobilized on porous, spherical, silica particles, 1–20 μm in diameter. | 直链淀粉三(3-氯苯基氨基甲酸酯)固定化于多孔球形硅胶颗粒,直径 1-20 μm。 |
| L127 | A crown ether chemically bonded to a 5-μm particle size silica gel substrate. The active site is (S)- pseudo-18-crown-6-ether. | 冠醚化学键合于 5 μm 粒径的硅胶基质上。活性位点为 (S)-假-18-冠-6-醚。 |
| L128 | Porous particles of polystyrene divinyl benzene with linear molecular weight operating range from 200–2,000,000 g/mol (polystyrene equivalent), 5 μm in diameter. | 聚苯乙烯-二乙烯苯多孔颗粒,线性分子量操作范围 200-2,000,000 g/mol(按聚苯乙烯等效计),直径 5 μm。 |
| L129 | A hydroxide-selective, sodium and potassium complexing resin consisting of a cryptand molecule bonded to 5-μm macroporous particles with an average pore size of 100 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. | 氢氧根选择性、钠和钾络合树脂,由穴醚分子键合于 5 μm 大孔颗粒组成;颗粒平均孔径 100 Å,由乙基乙烯苯与 55% 二乙烯苯交联组成。 |
| L130 | Cellulose tris(3,5-dimethylphenylcarbamate) coated on 10-μm silica gel particles. | 纤维素三(3,5-二甲基苯基氨基甲酸酯)涂覆于 10 μm 硅胶颗粒上。 |
| L131 | Amylose tris-(3,5-dichlorophenylcarbamate), immobilized on porous, spherical, silica particles, 3–20 μm in diameter | 直链淀粉三(3,5-二氯苯基氨基甲酸酯)固定化于多孔球形硅胶颗粒,直径 3-20 μm。 |
USP 填料代号(L 组)× 可供品牌对照表 数据源:USP–NF 2025 官方代号定义,共 131 条(G/S 组为 GC 用途,已剔除)。可供产品覆盖麦可旺志全部成品柱品牌——自营 HPLCONE / COSMOSIL / ChiralOne 与一级代理 Fortis / Shodex / Shinwa / L-column;HPLCONE、COSMOSIL 附真实型号/货号(COSMOSIL 取 4.6×250mm 代表货号),代理品牌给系列名+型号询价。当前 可提供 103 条、暂无对应 20 条(短链 C1–C6/C12/C30、氧化铝、石墨碳、混合模式等)、未收录 8 条。用下方品牌勾选器与 L 号输入框可快速筛选。
| 代号 | 英文定义(USP 原文) | 中文释义 | 可提供产品(按品牌) |
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数据说明:L 组中 8 条代号(L71、L73、L107、L108、L111、L115、L116、L117)在 USP 2025 未收录填料定义,按"未收录"标注。代理品牌相态覆盖依据原厂产品线(Fortis Evosphere/SpeedCore、Shodex SUGAR/SEC/IC/HILIC、Shinwa ULTRON ES/VX/PS·STR、L-column ODS/C8/Phenyl),具体型号与货号以正式代理报价为准。自营 HPLCONE/COSMOSIL 货号取自公司真实产品库。